qianyuan wang duke

0000000556 00000 n Qianben received a 2010 Young Investigator Award from Society for Basic Urologic Research. January 2016 and Ph.D. degrees from China Academy of Medical Sciences and Peking Union Medical College. As Rebecca MacKinnon points out, there is a strong tradition in China of setting the masses on local officials to fight corruption. Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. Duke researchers edit genes to prevent, treat COVID-19 in the lab. , Lupien, Mathieu, Jrme Eeckhoute, Clifford A. Meyer, Qianben Wang, Yong Zhang, Wei Li, Jason S. Carroll, X Shirley Liu, and Myles Brown. Importantly, MED1 phosphorylation increases during prostate cancer progression to the lethal phase, and pharmacological inhibition of CDK9 decreases prostate tumor growth by decreasing MED1 phosphorylation and Pol II recycling. Omega-3 or n-3 polyunsaturated fatty acids (PUFAs) are widely studied for health benefits that may relate to anti-inflammatory activity. Our results indicate that targeting lung protease mRNA by Cas13d nanosystem represents a unique strategy for controlling SARS-CoV-2 infection and demonstrate that CRISPR can be used as a potential treatment for SARS-CoV-2 infection. , McNair, C., A. Urbanucci, C. E. S. Comstock, M. A. Augello, J. F. Goodwin, R. Launchbury, S. G. Zhao, et al. We will work with Dr. Herman Staats (PI) to compare vaccine adjuvants for their ability to modulate epigenetic regulation of gene expression. Dietary omega-3 fatty acid intake impacts peripheral blood DNA methylation -anti-inflammatory effects and individual variability in a pilot study. University of Texas Health Science Center at San Antonio. from Tianjian Medical University and his Ph.D. degree from National Cancer Center/Cancer Hospital, China Academy of Medical Sciences and Peking Union Medical College in 2020. , Hankey, William, Zhong Chen, and Qianben Wang. Wang Qianyuan, a Chinese student studying at Duke University in the US, also experienced the wrath of human flesh searchers. , Wang, Qianben, T. S. Udayakumar, Tadas S. Vasaitis, Angela M. Brodie, and Joseph D. Fondell. Mechanistically, MED31 mediates the recycling of phosphorylated MED1 and Pol II, enhancing mRNA output during the transcription recycling process. Of interest is the emerging role of fatty acids to impact DNA methylation (DNAm) and thereby modulate mediating inflammatory processes. Qianyuan Wang, Actor: Jie jiu Wu xian sheng. Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710 Contact Contact Us 888-ASK-DUKE (888-275-3853 . Duke Cancer Center Cary Radiation Oncology, Duke Regional Hospital Colorectal Surgery, DCI Center for Prostate & Urologic Cancers, Office of Cancer Research Career Development (OCRCD), Duke Supportive Care & Survivorship Center, https://scholars.duke.edu/person/Qianben.Wang. Chinese human flesh search engines are examples of netizen vigilantism. , Li, Yanjing, Yiping He, William Butler, Lingfan Xu, Yan Chang, Kefeng Lei, Hong Zhang, et al. Atomically dispersed CuN4 moieties were confirmed by hi We defend the internet and other systems of communication against illegitimate encroachments by both public and private powers. Pathway analysis identified significantly hypermethylated signaling networks after n-3 PUFA treatment, such as the Toll-like Receptor inflammatory pathway. Dr. Qianben Wang earned his Ph.D. in 2002 from the University of Maryland School of Medicine under the supervision of Dr. Joseph Fondell. Free Speech Debate is a research project of the Dahrendorf Programme for the Study of Freedom at St Antony's College in the University of Oxford. Will it work in people? She obtained her Ph.D. in Pharmaceutical Sciences from University of Maryland at Baltimore and did her postdoc training at Brigham and Womens Hospital & Harvard Medical School. Proof-of-principle experiments identified PAF1 complex components among recycling factors and detected defective transcriptional output from Pol II recycling following PAF1 depletion. A detective tracks down a gang of criminals ten years after they initially evaded arrest. Qianben Wang Laboratory is powered by WordPress at Duke WordPress Sites. He subsequently moved to the Ohio State University, where he held positions as Postdoctoral Fellow (20082012), Research Scientist (20122016), and Senior Research Scientist (20162017). Prostate Cancer Cell Phenotypes Remain Stable Following PDE5 Inhibition in the Clinically Relevant Range. , Horning, Aaron M., Yao Wang, Che-Kuang Lin, Anna D. Louie, Rohit R. Jadhav, Chia-Nung Hung, Chiou-Miin Wang, et al. , Lee, Ying-Ying, Myth Ts Mok, Wei Kang, Weiqin Yang, Wenshu Tang, Feng Wu, Liangliang Xu, et al. , Wu, Dayong, Benjamin Sunkel, Zhong Chen, Xiangtao Liu, Zhenqing Ye, Qianjin Li, Cassandra Grenade, et al. Yet, there are certain similarities, such as the feeling of responsibility towards society, the wish to fight injustice and corruption, especially in the case of party officials. Qian Wang, D.O. His recent studies are designed to combine CRISPR/Cas13 technologies with nanotechnology to target undruggable transcription factors in cancers and host proteases for controlling SARS-CoV-2 infection. Center PIs presented project progress at the virtual meeting. We don't have much information about He's past relationship and any previous engaged. Please read them with this in mind. Qianyuan Wang was born on June 23, 1972 in Shenyang, Liaoning, China. Welcome, Jinjin! Not kidding. , Chen, Zhong, Dayong Wu, Jennifer M. Thomas-Ahner, Changxue Lu, Pei Zhao, Qingfu Zhang, Connor Geraghty, et al. , Chen, Zhong, Liguo Wang, Qianben Wang, and Wei Li. December 2011 "I don't think the parents of Wang Qianyuan should take the blame for whatever the girl does abroad," said Lou Gan, another colleague of Wang. Welcome, Furong! Duke researchers say new method to prevent/treat COVID shows promise in animal studies, Scientists study a mutation-proof treatment for COVID-19, New treatment in development at Duke shows promise against COVID-19. 7 times. Helen Haft explains how the Orthodox Church has eroded freedom of the media and lobbied for the 2013 law against offending religious feelings. Yang Tao, a government prosecutor from Jiangxi province explained in Shanghais Oriental Morning Post in 2008 that human flesh searches are a necessary avenue for ordinary citizens to seek justice. Bills paper entitled Prostate cancer cell phenotypes remain stable following PDE5 inhibition in the clinically relevant range was accepted by Translational Oncology. Prostate tumors exhibited enhanced transcriptional recycling, which was attenuated by antibody-based PAF1 depletion. Reported by Duke Pathology News: Chen Receives National Cancer Institute R50 Research Specialist Award.. +4QDn"L0(faL)z.jyFc.X#f:jY&a!qX$iTM?c After the 2008 earthquake in Sichuan, Zhang Ya posted a video of herself online, complaining that her favourite TV shows were interrupted by the earthquake reportage. June 2012 Driving Directions. Welcome, Bill! Ben earned his PhD in Biochemistry upon successful defense of his dissertation entitled Looking beyond the androgen receptor for transcriptional drivers of prostate cancer.. CRISPR technology demonstrates success in preventing and treating COVID, Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections, CRISPR Technology Demonstrates Success in Preventing and Treating COVID, Dynamic nucleosome landscape elicits a novel noncanonical GATA2 pioneer model, Qianben was appointed to NIH Cancer Molecular Pathobiology (CAMP) Study Section, Phosphorylated MED1 links transcription recycling and cancer growth, Dr. Qianben Wang receives Mike Slive Foundation Award. , Zhang, Chunpeng, Liguo Wang, Dayong Wu, Hongyan Chen, Zhong Chen, Jennifer M. Thomas-Ahner, Debra L. Zynger, et al. Reported by Duke University School of Medicine News and Communications and Reprinted on Duke Pathology News: Researchers Identify Promising New Drug Target for Lethal Prostate Cancer. He is co-mentored by Dr. Shili Lin at the Department of Statistics. , Zhang, Yuexing, Joseph D. Fondell, Qianben Wang, Xianmin Xia, Aiwu Cheng, Michael L. Lu, and Anne W. Hamburger. The title of his talk was Epigenomic approaches to discover transcriptional vulnerabilities of prostate cancer. Will it work in people? Bills paper entitled Prostate cancer cell phenotypes remain stable following PDE5 inhibition in the clinically relevant range was the most downloaded, Chen Receives National Cancer Institute R50 Research Specialist Award., Yuan Receives DoD Early Investigator Research Award, https://pathology.duke.edu/news/wang-co-organizes-san-antonio-duke-cancer-systems-biology-symposium, http://molecularmedicine.uthscsa.edu/CSBC_U54.aspx, Duke Pathology Featured at AACR Meeting in Atalanta, New Postdoc fellows ready to dive into genomic research, Hankey Selected NIH T32 Post-Doc Training Program, Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13, HoxB13 mediates AR-V7 activity in prostate cancer, Researchers Identify Promising New Drug Target for Lethal Prostate Cancer, Research Points to Promising New Target in Prostate Cancer, https://www.cancer.gov/about-nci/organization/dcb/research-programs/csbc/announcement. , Chen, Zhong, Xun Lan, Dayong Wu, Benjamin Sunkel, Zhenqing Ye, Jiaoti Huang, Zhihua Liu, Steven K. Clinton, Victor X. Jin, and Qianben Wang. Zhifens paper entitled Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection was accepted by Nature Chemical Biology. Yuan Wang Assistant Professor of International Relations at Duke Kunshan University Current Appointments & Affiliations Assistant Professor of International Relations at Duke Kunshan University, DKU Faculty , Duke Kunshan University 2022 Assistant Professor of the Practice, DKU Visiting Faculty , Duke University 2022 Contact Information What followed was a public outcry and human flesh search for the ex-husband, Wang Fei, and his girlfriend. , Lan, Xun, Heather Witt, Koichi Katsumura, Zhenqing Ye, Qianben Wang, Emery H. Bresnick, Peggy J. Farnham, and Victor X. Jin. from Capital University of Medical Sciences and M.S. Reported by Duke Daily, Duke Health and Duke Pathology News: " CRISPR Technology Demonstrates Success in Preventing and Treating COVID". Dr. Wang joined the Department of Pathology at Duke University School of Medicine as a Professor with tenure in December, 2017. We must be empowered to challenge all limits to freedom of information justified on such grounds as national security. Qianben obtained his OSU pelotonia idea grant. He won Best Actor at the 23rd Tokyo International Film Festival for his role in the movie, The Piano in a Factory . 27 0 obj<>stream Here we describe a chemically engineered nanosystem encapsulating CRISPR-Cas13d, developed to specifically target lung protease cathepsin L (Ctsl) messenger RNA to block SARS-CoV-2 infection in mice. Energy Restriction-mimetic Agents Induce Apoptosis in Prostate Cancer Cells in Part through Epigenetic Activation of KLF6 Tumor Suppressor Gene Expression. We must be able to protect our privacy and to counter slurs on our reputations, but not prevent scrutiny that is in the public interest. Watch on Apple devices, streaming platforms, and smart TVs. In this pilot study, we investigated the impact of n-3 PUFA intake on DNAm in inflammation-related signaling pathways in peripheral blood mononuclear cells (PBMCs) of women at high risk of breast cancer. Ben received an award for Outstanding Poster Presentation at the annual Life Sciences Interdisciplinary Graduate Programs (IGP) Symposium. June 2011 Several other posts followed, showing Zhou wearing a Vacheron-Constantin watch worth about 10,000 and driving a Cadillac. Duke University https://scholars.duke.edu/individual/pub1515961. Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. Wang Qianyuan Written in the early morning of 10 April 2008 . With Qianyuan Wang, Daniel Wu, Jessie Li, Michelle Wai. We moved to a new lab space at Room 1014, GSRB1!! Clearly the Chinese government have weighed the risks / rewards. Dr. Wang becomes the prostate cancer project leader. Eric Heinze argues that it is contradictory to the principles of free speech to criticise the Israeli ambassador to Britain online and then no-platform him at a university talk. Qianben received a 2012 Endocrine Society Early Investigators Award. 2004 - 20073 years. She has been working as research scientist at Ohio State University Comprehensive Cancer Center since 2008 before joining Wangs group at Duke in 2017 as a senior research scientist and lab manager. The Role of microRNA-221 and microRNA-222 in Androgen-Independent Prostate Cancer Cell Lines, Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells, Target Gene-Specific Regulation of Androgen Receptor Activity by p42/p44 Mitogen-Activated Protein Kinase, Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes, FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription, A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth, Genome-wide analysis of estrogen receptor binding sites, Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking, Mechanistic Relationship between Androgen Receptor Polyglutamine Tract Truncation and Androgen-dependent Transcriptional Hyperactivity in Prostate Cancer Cells, A Coregulatory Role for the TRAP-Mediator Complex in Androgen Receptor-mediated Gene Expression, Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1, Generation of a Mammalian Cell Line Stably Expressing a Tetracycline-Regulated Epitope-Tagged Human Androgen Receptor: Implications for Steroid Hormone Receptor Research, Specific Structural Motifs Determine TRAP220 Interactions with Nuclear Hormone Receptors, Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710. While they can empower citizens in the face of corrupt officials, they can also serve those who wish to limit the freedom of speech of those they disagree with. Qianben, Furong and Zhifen attended The 30th Society for Basic Urologic Research (SBUR) Annual Meeting, November 11-13, 2022. Please read the Duke Wordpress Policies. Gender . The New York Times even refers to human flesh searches as Red Guards 2.0. Dr. Zhong Chen was appointed Assistant Professor in Pathology on December 1, 2017. We allow no taboos against and seize every chance for the spread of knowledge. In 1997, she became the first woman to be elected as a prime minister in China. Dr. Qianben Wang earned his Ph.D. in 2002 from the University of Maryland School of Medicine under the supervision of Dr. Joseph Fondell. Cassandra Grenade joined the Wang lab as a postdoctoral fellow. , Wang, Qianben, Dipali Sharma, Yunsheng Ren, and Joseph D. Fondell. In this study, we generate over three billons of multi-omics sequencing data to exploit dynamic nucleosome landscape governed by pioneer factors (PFs), FOXA1 and GATA2. Chunpeng published an article entitled Definition of a FoxA1 Cistrome That Is Crucial for G1 to S-Phase Cell-Cycle Transit in Castration-Resistant Prostate Cancer in Cancer Research. Take a look at the highlighted principles which are relevant to this article to find out more, or browse all of our key principles. Iginio Gagliardone explores the surprising technopolitics of two competing visions of the internet, US and Chinese, in Ethiopia. | Terms of Use | , He, Housheng Hansen, Clifford A. Meyer, Hyunjin Shin, Shannon T. Bailey, Gang Wei, Qianben Wang, Yong Zhang, et al. Our laboratory is located in the School of Medicine atDuke University, and is part of Duke Pathology, Duke Cancer Institute, and National Cancer Institute (NCI) funded San Antonio-Duke University Research Center for Cancer Systems Biology(SA-Duke RCCSB). Qianben was awarded a pilot grant from Duke Cancer Institute. , Wang, Qianben, Jason S. Carroll, and Myles Brown. Qianben served as a co-chair of the Nuclear Receptor Function and Co-factors session of the Gordon Research Conference on Hormone-Dependent Cancers (Newry, Maine). Dynamic nucleosome landscape elicits a noncanonical GATA2 pioneer model. Zhenqing and Zhongs paper entitled Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors was accepted by Nucleic Acids Research. We further show that this approach extends survival of mice lethally infected with SARS-CoV-2, correlating with decreased lung virus burden, reduced expression of proinflammatory cytokines/chemokines and diminished severity of pulmonary interstitial inflammation. , Cui, Zhifen, Cong Zeng, Furong Huang, Fuwen Yuan, Jingyue Yan, Yue Zhao, Yufan Zhou, et al. Qianben was invited to deliver a talk at The Ohio State University. %%EOF Welcome to Qianben Wangs laboratory. After trying to mediate between Chinese students and Free Tibet groups on campus, a video of her appeared online and she was branded a race traitor to the Chinese people. Welcome, Kathryn! Dr. Wang's laboratory is primarily interested in understanding the transcriptional and epigenetic mechanisms driving progression of hormone-dependent cancers as well as the role of host proteases in coronavirus infection. More media outlets picked up our CRISPR-SARS-CoV-2 story and run the following features. 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